82395 6 Reasons We Have to Say a Study Was "In Mice"

6 Reasons We Have to Say a Study Was “In Mice”


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A lot of our videos include the disclaimer "Mice aren't people." But why do we keep saying this, and if rodent studies aren't effective, why do we keep using them? Hosted by: Stefan Chin SciShow has a spinoff podcast! It's called SciShow Tangents. Check it out at http://www.scishowtangents.org
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Sources: Intro:
https://www.genome.gov/10005834/background-on-mouse-as-a-model-organism Alzheimer's disease:
https://www.nia.nih.gov/health/what-happens-brain-alzheimers-disease https://www.nature.com/articles/d41586-018-05722-9 https://www.biospace.com/article/a-look-at-biogen-s-big-bet-on-the-holy-grail-of-science-and-mdash-alzheimer-s-/ http://investors.biogen.com/news-releases/news-release-details/biogen-and-eisai-discontinue-phase-3-engage-and-emerge-trials https://www.nature.com/articles/s41586-019-1506-7 Multiple sclerosis:
https://medlineplus.gov/multiplesclerosis.html https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154595/ https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(87)92863-7/fulltext https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586507/ https://www.degruyter.com/view/j/revneuro.2019.30.issue-1/revneuro-2018-0002/revneuro-2018-0002.xml Hepatitis B:
https://www.cdc.gov/hepatitis/hbv/index.htm https://www.nap.edu/catalog/4887/review-of-the-fialuridine-fiau-clinical-trials http://discovermagazine.com/1994/mar/thecurethatkille345 https://www.ncbi.nlm.nih.gov/pubmed/16595656 http://perspectivesinmedicine.cshlp.org/content/5/12/a021451.full Tuberculosis: https://www.cdc.gov/tb/publications/faqs/qa_introduction.htm
https://medlineplus.gov/tuberculosis.html https://www.ncbi.nlm.nih.gov/pubmed/11288517 https://www.ncbi.nlm.nih.gov/pubmed/20819249 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798013/
https://www.jimmunol.org/content/172/5/2731#sec-6 Saccharin:
https://www.nytimes.com/1977/06/19/archives/fda-says-new-canadian-study-reinforces-its-ban-of-saccharin.html https://academic.oup.com/annonc/article/15/10/1460/170200 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009921/ https://www.ncbi.nlm.nih.gov/pubmed/9428778 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591507/ https://www.niehs.nih.gov/news/newsroom/releases/2000/may15/index.cfm https://www.foodserviceandhospitality.com/health-canada-approves-saccharin-sweeteners-canada/ Microbiome:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991899/ https://www.nature.com/articles/s41598-018-24342-x#Sec8 https://www.health.harvard.edu/blog/stool-transplants-are-now-standard-of-care-for-recurrent-c-difficile-infections-2019050916576
https://dmm.biologists.org/content/8/1/1#sec-16 https://www.the-scientist.com/news-opinion/mouse-genetics-shape-the-gut-microbiome-more-than-their-environment-66238 https://www.eurekalert.org/pub_releases/2019-08/niod-mc072919.php Closing:
https://www.nabr.org/animal-research-into-the-worlds-five-deadliest-diseases/ https://commons.wikimedia.org/wiki/File:Neuron.svg https://commons.wikimedia.org/wiki/File:1FG9_IFNG_IFNG.png#/media/File:1FG9_IFNG_IFNG.png

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