82729 What Your Family History Can’t Tell You

What Your Family History Can’t Tell You





Thanks to the National Human Genome Research Institute for supporting this episode. If you’re interested in learning more about the human genome and the latest in polygenic risk score research, head to http://genome.gov/PRS #polygenicriskscores #science The first time you visit a new doctor, they’ll probably ask you about your family history – but it turns out that family history doesn’t tell you everything about the risks that can be hidden in your genes. Hosted by: Hank Green SciShow has a spinoff podcast! It's called SciShow Tangents. Check it out at http://www.scishowtangents.org
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Sources:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987426/
https://academic.oup.com/hmg/article/23/22/6112/2900819
https://www.broadinstitute.org/news/depth-polygenic-risk-scoring
https://www.nature.com/articles/s41588-018-0183-z
https://jamanetwork.com/journals/jama/article-abstract/2730627
https://www.bmj.com/content/360/bmj.j5757
https://www.nature.com/articles/s41576-018-0018-x
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309089/
https://www.genome.gov/about-genomics/fact-sheets/Genome-Wide-Association-Studies-Fact-Sheet Image Sources:
https://commons.wikimedia.org/wiki/File:PBB_Protein_BRCA2_image.jpg
https://commons.wikimedia.org/wiki/File:Protein_BRCA1_PDB_1jm7.png
https://commons.wikimedia.org/wiki/File:Manhattan_Plot.png
https://commons.wikimedia.org/wiki/File:Dna-SNP.svg

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